Research Areas

Canada


Genzyme's research is oriented around medical areas where we feel new therapies can have a significant impact, emphasizing our primary areas of focus – rare diseases and neuroimmunological disorders such as multiple sclerosis.

A Focus on Clinical Needs

Genzyme's R&D efforts span a range of clinical needs. Often our research focuses on rare, or orphan, diseases that get little attention elsewhere. Other times it's in more widely studied medical areas, but focused on a specific niche or novel treatment approach.

We have particularly strong research programs in rare diseases and neuroimmunological disorders such as multiple sclerosis. We are on the forefront of solving medical challenges within these therapeutic areas.

For example, most medicines that treat lysosomal storage disorders (LSDs) are infusions that can’t treat the iterations of these diseases that affect the central nervous system. Our scientists are currently investigating a small molecule for Fabry disease that has the potential to reach the central nervous system. If successful, this approach could be used with other diseases and could revolutionize the treatment of neuropathic LSDs for a group of patients who had no treatment options.

Within neuroimmunology, we are working on next-generation MS treatments. Our goal is to find treatments that not only stop disease progression but also repair the damaged immune system, and we are researching a variety of technologies – including small molecules and antibodies – to accomplish this goal.

We also pursue promising research outside our defined areas of focus; these product candidates may eventually be commercialized by another part of Sanofi.

Our primary research areas include:

  • Genetic Diseases – such as lysosomal storage disorders, cystic fibrosis, myotonic dystrophy, hemophilia, spinal muscular atrophy, Huntington’s disease
  • Neurologic Diseases – such as neuropathic LSDs, Parkinson's disease, Huntington's disease, age-related macular degeneration, amyotrophic lateral sclerosis, spinal muscular atrophy
  • Neuroimmunology – such as multiple sclerosis, autoimmune neurological disorders
  • Immune-Mediated Diseases – such as lupus, giant cell arteritis, type I diabetes, inflammatory bowel disease
  • Cardiovascular Diseases – such as severe dyslipidemia, familial hypercholesterolemia, acute myocardial infarction
  • Renal Diseases – such as chronic kidney disease, polycystic kidney disease, acute kidney injury
  • Orthopedics – such as osteoarthritis, cartilage injury/defects

Applying Innovative Technologies

With one of the industry's most diverse arrays of medical technology platforms at their disposal, Genzyme's scientists can leverage a wide range of both biologic and chemical approaches to find the best possible therapeutic solution to treat a particular disease. The optimal format to meet physician and patient needs may even be a combination of platforms.

We have brought products to market in all of the following technology areas except gene therapy, a still developing field in which we have industry-leading research and development efforts:

  • Protein-Based Therapies
  • Therapeutic Polymers
  • Small Molecules
  • Biomaterials
  • Gene Therapies
Last Updated: 12/3/2015
Contact

Genzyme Canada
Canadian Office 
2700 Matheson Blvd. East 
West Tower, Suite 800 
Mississauga, Ontario L4W 4V9 
Canada 
Tel: +1 905 625 0011 
Fax: +1 905 625 7811 
Toll Free: +1 877 220 8918 
Email

Genzyme Medical Information 
Tel: +1 800 589 6215
Email

If this is an emergency, please contact your local emergency department.

Ethics inquiries 
Tel: +1 800 648 1297

Careers
Explore opportunities at a company that's as committed to our employees as we are to our patients.

infoBox